Additional file 4 of Layer-specific molecular signatures of colon anastomotic healing and leakage in mice

Additional file 4: Figure S3 A Enrichment plots of Type I IFN and IFNγ response in the M/SM layer of the anastomotic tissue at 6h compared to naive controls. B Significantly enriched gene ontology terms related to vascularisation pathways in the M/SM tissue of anastomosis at 6h after surgery compared to naïve conditions. C Heatmap of HIF-1a-target genes expressed in the M/SM layer of anastomotic tissue at 6h, 24h and 72h and naïve animals based on GSEA. D Significantly enriched gene ontology terms related to vascularisation pathways in the ME tissue of anastomosis at 6h after surgery compared to naïve conditions. E Heatmap of HIF-1α-target genes expressed in the ME layer of anastomotic tissue at 6h, 24h and 72h and naïve animals based on GSEA.