Two new cadinane-type sesquiterpene glycosides from <i>Dendrobium findleyanum</i>
Two novel and two previously identified cadinane-type sesquiterpene glycosides, findleyanosides E-F (<b>1</b>-<b>2</b>), balanoindicoside B (<b>3</b>) and pumilaside C (<b>4</b>), were extracted from the <i>Dendrobium findleyanum</i> stems. The establishment of structures was mainly conducted <i>via</i> spectroscopic techniques and by comparing with literature data. Electronic circular dichroism (ECD) computations helped determine the absolute configuration of the novel molecules. All molecules exhibited moderate cytotoxic effects against A-549 human tumour cell lines, with IC<sub>50</sub> values of 15.52, 17.68, 13.85 and 16.64 <i>μ</i>M, respectively.
Publication Details
- Journal
- Figshare
- Published
- 2025-01-01
- DOI
- https://doi.org/10.6084/m9.figshare.29891165.v1
- Primary Topic
- Machine Learning in Bioinformatics
- Type
- article
- Field-Weighted Citation Impact
- 0.00