A facile synthesis of tricyclic compounds consisting of benzo thiazol-selenazol skeletons <i>via</i> the copper‐catalyzed four-component reactions

A rapid, efficient, and simple ultrasonic-assisted protocol is reported for the synthesis of benzo thiazol-selenazol skeletons from the one-pot reactions of acyl iso (seleno or thio) cyanate, benzothiazole and various terminal alkynes, in the vicinity of a copper catalyst, without the help of additional ligands under ultrasonic conditions for 45 min with good efficiency. The role of ultrasound in this reaction is to reduce the time, increase the efficiency of product preparation, and make the work-up easier. The use of simple and available raw materials, mild copper catalytic reaction conditions, easy purification with the help of a solvent, and finally, the synthesis of 10 new compounds from the benzo thiazol-selenazol family are notable features of this protocol.

Publication Details

Journal
Figshare
Published
2025-01-01
DOI
https://doi.org/10.6084/m9.figshare.29912259
Primary Topic
Organoselenium and organotellurium chemistry
Type
article
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article

A facile synthesis of tricyclic compounds consisting of benzo thiazol-selenazol skeletons via the copper‐catalyzed four-component reactions

Figshare
Organoselenium and organotellurium chemistry
article

A facile synthesis of tricyclic compounds consisting of benzo thiazol-selenazol skeletons via the copper‐catalyzed four-component reactions

article en

Abstract

A rapid, efficient, and simple ultrasonic-assisted protocol is reported for the synthesis of benzo thiazol-selenazol skeletons from the one-pot reactions of acyl iso (seleno or thio) cyanate, benzothiazole and various terminal alkynes, in the vicinity of a copper catalyst, without the help of additional ligands under ultrasonic conditions for 45 min with good efficiency. The role of ultrasound in this reaction is to reduce the time, increase the efficiency of product preparation, and make the work-up easier. The use of simple and available raw materials, mild copper catalytic reaction conditions, easy purification with the help of a solvent, and finally, the synthesis of 10 new compounds from the benzo thiazol-selenazol family are notable features of this protocol.

Figshare
Openalex Percentile: Top 49%
Organoselenium and organotellurium chemistry
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