<i>Supplemental Figure 2: Prenatal Anti-myostatin Antibody Therapy; E17.5 Fetuses and </i><i>µ</i><i>CT.</i>

Fetal weights and whole fetal µCT from WT (circles) and +/oim (squares) treated dams were assessed at P-E17.5 and P-D21. Dams were prenatally treated with Ctrl-Ab (Regn1945, black symbols) or Mstn-Ab (Regn647, purple symbols for fetal offspring, blue symbols for dams). Female fetal body weights (mg) from P-E17.5 (A) WT dams (fetal genotypes [WT and +/oim]) and (B) +/oim dams (fetal genotypes: [WT, +/oim, and oim/oim]) (n=6-17). Fetal body weights are an average of averages per litter for same sex and genotype. Whole fetal µCT bone volume per total body volume of male fetuses from prenatally treated P-E17.5 (C) WT and (D) +/oim treated dams (n=3-9) and female fetuses from (E) WT and (F) +/oim treated dams (n=2-9). *p&lt; 0.05, **p&lt;0.01, ***p&lt;0.001, ****p&lt;0.0001 by two-way ANOVA with Tukey’s multiple comparisons tests and uncorrected Fisher’s LSD. Data are represented as mean ± S.E.M.