A new benzoate derivative from <i>Talaromyces fusiformis</i>, an endophytic fungus cultured from <i>Hypecoum leptocarpum</i> Hook. f. et. Thoms

A new benzoate derivative, 2, 3, 4, 5-tetrahydroxypentyl-4- (3-hydroxy-3-methylbutoxy) benzoate (1) and four known ones, including xylityl-4-hydroxybenzoates (2), fuscoatramide (3), talarodride H (4), and talarodride G (5) were isolated from <i>Hypecoum leptocarpum-</i>derived endophytic fungus <i>Talaromyces fusiformis</i> in this study. The compound structures were determined by means of UV, IR, HRESIMS, and NMR. The cytotoxic activities of these compounds were evaluated using the MTT assay. Talarodride G effectively inhibited human breast adenocarcinoma (MCF-7) cell lines with an IC₅₀ value of 24.97 μg/mL.