Supplementary tables CRH study

An intravenous bolus of 100µg CRH or placebo was administered in HVs in a crossover, double-blind, randomized fashion. Two hours later, a gastroscopy was performed to measure permeability in Ussing chambers and to count mast-cells and eosinophils on duodenal biopsies. Supernatant was assessed for eosinophil-derived neurotoxin(EDN), tryptase and chymase. In addition, CRH was administrated <i>ex-vivo</i> to baseline biopsies pretreated with or without lodoxamide;