Additional file 2 of Merging metabolomics and genomics provides a catalog of genetic factors that influence molecular phenotypes in pigs linking relevant metabolic pathways
Additional file 2: Table S4. List of metabolites in the kynurenine pathway (KP) analyzed in the pigs included in the nutrigenetic study and statistics of metabolites stratified by genotype and metabolic condition at the basal and after the tryptophan (Trp) supplementation. Description: Metabolomic data are obtained from the Bevital platform on plasma of Large White × Landrace piglets. Table S5. Systems of ordinary differential equations (ODE) used to model the kynurenine pathway. Description: Metabolites are those reported in Additional file 2: Table S4. Table S6. Information used in the kinetic modeling of the kynurenine pathway. Table S7. Human kinetic constants. Table S13. Distribution of the predicted consequences for variants identified from whole-genome resequencing of Large White, Duroc and Landrace pigs. Table S15. Variants altering the protein coding sequence of the KMO gene. Description: Variant constituting two major haplotypes are those and forming two major haplotypes. Table S16. Allele frequency of the KMO polymorphisms identified in several pig breeds and in wild boars. Table S17. Partial Correlation Coefficients (PCC) in Large White pigs before and after the inclusion of the genetic effect from the mQTL (genotype-corrected PCC) in the GGM construction. Description: Underlined, the PPC >0.3.
Institutions
- University of Bologna (IT)
Publication Details
- Journal
- Figshare
- Published
- 2025-01-01
- DOI
- https://doi.org/10.6084/m9.figshare.28551679
- Primary Topic
- Construction Management and Sustainability
- Type
- article
- Field-Weighted Citation Impact
- 0.00