Additional file 2 of Population-specific genetic-risk scores enable improved prediction of mortality within 28 days of sepsis onset: a retrospective Taiwanese cohort study

Supplementary material 2: Figure S1. Exclusion criteria and study samples included in the study. Figure S2. Heatmap showing tissue based differential expression analysis using FUMA for genes mapped from genome-wide significant SNPs. Figure S3. General tissue specific up-regulated and down-regulated genes mapped from genome-wide significant SNPs via FUMA. Figure S4. Detailed tissue specific up-regulated and down-regulated genes mapped from genome-wide significant SNPs via FUMA. Table S1. SNPs found previously to be associated with sepsis susceptibility in genome-wide association studies. Table S2. List of suggestively significant SNPs (p<1 x10-5). Table S3. The performance of the polygenic risk score in the Cox prediction model using clumping and thresholding method (C+T) parameters. Table S4. Characteristics associated with 28-day mortality in the training dataset. Table S5. Characteristics associated with 28-day mortality in the testing dataset.