Additional file 2 of Cardiac magnetic resonance markers of pre-clinical hypertrophic and dilated cardiomyopathy in genetic variant carriers

Additional file 2: Methods, Figure legends, Figures S1–S10. Methods—Additional methods. Figure legends—Full legends of Figs. S1–S10. Fig. S1 Loadings of the eight principal components explaining 90% of the variance in the CMR measurements. Fig. S2 Cumulative variance explained by the eight principal components explaining 90% of the CMR measurements. Fig. S3 Distribution of UK Biobank participants carrying pathogenic and likely pathogenic variants in cardiomyopathy-associated genes. Fig. S4 Survival of incident atrial fibrillation based on CMR measurements. Fig. S5 Survival of incident heart failure based on CMR measurements. Fig. S6 Spearman correlation between the effect estimates of the analyses on complete-case and imputed data. Fig. S7 Association of CMR measurements with HCM G + and the three most common HCM genes. Fig. S8 Association of CMR measurements with DCM G + and the three most common DCM genes. Fig. S9 Association of CMR measurements with the most common HCM genes. Fig. S10 Association of CMR measurements with the most common DCM genes.