Additional file 2 of Direct genetic transformation bypasses tumor-associated DNA methylation alterations
Additional file 2. Fig. S1: Characterization of different hyper CGI sets. Fig. S2: Methylated CGIs in healthy cell types Fig. S3: CGI hypermethylation metrics across different assays. Fig. S4: Global pan-cancer DNA methylation dynamics of melanoma models and patients. Fig. S5: Differentially methylated regions of patients or melanocyte models compared to control samples. Fig. S6: Global methylation depletion in senescence and transformation model. Fig. S7: Differentially methylated regions between tumor and healthy tissue in mouse models. Fig. S8: Transcriptional state of genes associated with hyper CGIs.
Institutions
- Broad Institute (US)
- Queen Mary University of London (GB)
- University of Potsdam (DE)
- Yale University (US)
- Massachusetts General Hospital (US)
- Dana-Farber Cancer Institute (US)
- Max Planck Institute for Molecular Genetics (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Figshare
- Published
- 2025-01-01
- DOI
- https://doi.org/10.6084/m9.figshare.29595465.v1
- Primary Topic
- Lattice Boltzmann Simulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00