Formulation & Evaluation of Antifungal Activity of Polyherbal Ointment in Animal Model

Polyherbal ointments are topical preparations that combine multiple medicinal herbs for enhanced therapeutic action. They target specific conditions like wound healing, pain relief, or skin care. Common types include wound healing ointments containing herbs like aloe vera, calendula, and turmeric, known for their antimicrobial and anti-inflammatory properties. Pain relief ointments use herbs like arnica, ginger, and eucalyptus, providing analgesic and anti-inflammatory effects. Skin care ointments may include neem, lavender, and chamomile, which can soothe and nourish the skin, potentially helping with conditions like eczema or acne. Anti-inflammatory ointments target inflammation and pain, while antifungal ointments treat fungal infections. Polyherbal ointments offer synergistic effects, reduced medication costs, and a natural alternative to conventional medications. However, it is important to be aware of potential allergies or sensitivities to specific herbs, consult with a healthcare professional before using a polyherbal ointment, and ensure the ointment is sourced from a reputable manufacturer and high-quality ingredients. The benefits of polyherbal ointments include synergistic effects, reduced medication costs, and a natural alternative to conventional medications. The study aims to assess the antifungal activity of a poly-herbal blend of Aloe vera leaves, cinnamon bark, and ginger rhizome using experimental animals. The objectives include conducting a literature survey, procuring and authenticating plant material, preparing the formulation, and evaluating its antifungal properties. From our previously reported results and results presented inhere it can be concluded, that Polyherbal Ointment (PHEO) and its components used showed very good therapeutic and antifungal effect in vitro and in vivo. These compounds could represent possible alternatives for the treatment of patients infected by dermatomycetes. Even more, because of the side effects of commercial fungicides and possible resistance of pathogens to the synthetic mycotics, the preparation with natural products have an advantage in treatment of fungal caused diseases. After all, facts, and the obtained results, it can be said that the advantage of products based on medicinal plants that were studied showed no harmful effects on humans and animals, and also proved to be very good antifungal and therapeutic agents.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-17
DOI
https://doi.org/10.5281/zenodo.15449114
Primary Topic
Atmospheric Ozone and Climate
Type
article
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article

Formulation & Evaluation of Antifungal Activity of Polyherbal Ointment in Animal Model

Zenodo (CERN European Organization for Nuclear Research)
Atmospheric Ozone and Climate
article

Formulation & Evaluation of Antifungal Activity of Polyherbal Ointment in Animal Model

article en

Abstract

Polyherbal ointments are topical preparations that combine multiple medicinal herbs for enhanced therapeutic action. They target specific conditions like wound healing, pain relief, or skin care. Common types include wound healing ointments containing herbs like aloe vera, calendula, and turmeric, known for their antimicrobial and anti-inflammatory properties. Pain relief ointments use herbs like arnica, ginger, and eucalyptus, providing analgesic and anti-inflammatory effects. Skin care ointments may include neem, lavender, and chamomile, which can soothe and nourish the skin, potentially helping with conditions like eczema or acne. Anti-inflammatory ointments target inflammation and pain, while antifungal ointments treat fungal infections. Polyherbal ointments offer synergistic effects, reduced medication costs, and a natural alternative to conventional medications. However, it is important to be aware of potential allergies or sensitivities to specific herbs, consult with a healthcare professional before using a polyherbal ointment, and ensure the ointment is sourced from a reputable manufacturer and high-quality ingredients. The benefits of polyherbal ointments include synergistic effects, reduced medication costs, and a natural alternative to conventional medications. The study aims to assess the antifungal activity of a poly-herbal blend of Aloe vera leaves, cinnamon bark, and ginger rhizome using experimental animals. The objectives include conducting a literature survey, procuring and authenticating plant material, preparing the formulation, and evaluating its antifungal properties. From our previously reported results and results presented inhere it can be concluded, that Polyherbal Ointment (PHEO) and its components used showed very good therapeutic and antifungal effect in vitro and in vivo. These compounds could represent possible alternatives for the treatment of patients infected by dermatomycetes. Even more, because of the side effects of commercial fungicides and possible resistance of pathogens to the synthetic mycotics, the preparation with natural products have an advantage in treatment of fungal caused diseases. After all, facts, and the obtained results, it can be said that the advantage of products based on medicinal plants that were studied showed no harmful effects on humans and animals, and also proved to be very good antifungal and therapeutic agents.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 49%
Atmospheric Ozone and Climate
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Formulation & Evaluation of Antifungal Activity of Polyherbal Ointment in Animal Model · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS