Hematological profile of hospitalized children in post-COVID-19 infection state

Coronavirus Disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the first global pandemic of the 21-th century. Even though the COVID-19 public health emergency ended, COVID-19 continues to be a health risk. COVID-19 in children appeared early in the pandemic. Children were less affected or suffered from milder disease than adults, however soon after multisystem inflammatory syndrome emerged. This study aims to explore hematological findings in hospitalized children presented in post SARS CoV-2 infection state. Of the 87 children included in the study 55% had leukocytosis, 58% had thrombocytosis, 66% had elevated CRP, 62% had elevated Fibrinogen, 37% had elevated Ferritin, and 32% had elevated D-dimer. The hemostatic system is mostly affected by the Multisystem Inflammatory Syndrome in children that follows SARS CoV-2 infection, leukocytosis, elevated CRP, Fibrinogen, Ferritin, and D-dimer are the most common findings. A careful monitoring of hematological and inflammatory parameters is recommended while evaluating children with MIS-C.