CHO Cell Antibody Drug Production

Therapeutic antibodies are highly regarded for their high affinity, specificity, low immunogenicity, and ability to target a wide range of biological molecules. Currently, mammalian cells, including Sp2/0, NS0, HEK293, and CHO cells, are primarily used for the production of therapeutic antibodies, with CHO cells accounting for over 70% of the production due to their complex posttranslational modification capabilities.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-02-27
DOI
https://doi.org/10.5281/zenodo.14935800
Primary Topic
Viral Infectious Diseases and Gene Expression in Insects
Type
article
Field-Weighted Citation Impact
0.00
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article

CHO Cell Antibody Drug Production

Zenodo (CERN European Organization for Nuclear Research)
Viral Infectious Diseases and Gene Expression in Insects
article

CHO Cell Antibody Drug Production

article en

Abstract

Therapeutic antibodies are highly regarded for their high affinity, specificity, low immunogenicity, and ability to target a wide range of biological molecules. Currently, mammalian cells, including Sp2/0, NS0, HEK293, and CHO cells, are primarily used for the production of therapeutic antibodies, with CHO cells accounting for over 70% of the production due to their complex posttranslational modification capabilities.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 53%
Viral Infectious Diseases and Gene Expression in Insects
DOIOpen Access PDFOpenAlex
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CHO Cell Antibody Drug Production · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS