Bempedoic Acid in Hypercholesterolemia Management: A New Approach

Hypercholesterolemia, is a condition that increase cholesterol levels in body and it is major risk factor for cardiovascular disease (CVD). In the treatment of this condition statins, bile acid sequestrants, and cholesterol absorption inhibitors are use but they show side effects especially statin are cause muscle-related complications. Bempedoic acid is new drug that lower the lipid and it is alternative of other medicine. It is use in statin-intolerant patients or those with familial hypercholesterolemia. Bempedoic acid inhibit ATP- citrate lyase which is produce factor of cholesterol and reduce level of LDL-C without any muscle-related adverse effects which are show in statins. This review article explores Bempedoic acid’s mechanism of action, its clinical efficacy in management of hypercholesterolemia, and its potential as a complementary or alternative therapy to traditional lipid-lowering treatments. Given its unique mechanism, Bempedoic acid offers a valuable advancement in the pharmacological management of hypercholesterolemia and cardiovascular risk.