A Review on Multi-Unit Particulate System: Advanced Technology for Novel Drug Delivery System

Pellets are agglomerates of fine powders or granules of bulk drugs and excipients typically ranging from about 0.5 to 1.5 mm. Multi-unit Particulates System technology refers to a pharmaceutical formulation approach in which a single dosage form, such as a tablet or capsule, contains multiple small, discrete pellets or granules. Each pellet acts as an individual drug delivery unit, often coated with one or more layers that control the release rate of the active pharmaceutical ingredient. Multi-Unit Particulate System consists of embedding many small pellet within one formulation. Types of Multi-Unit Particulate System one comprising of coated pellets (reservoir systems), and the other prepared by compaction of matrix and/or uncoated drug pellets.