COMPARATIVE CHARACTERISTICS OF CLASSICAL AND NEW ORAL ANTICOAGULANTS

This article presents a comparative analysis of classical and new oral anticoagulants, highlighting their mechanisms of action, pharmacokinetic properties, clinical applications, advantages, and limitations. Classical anticoagulants, such as warfarin, have been widely used for decades but require regular monitoring and dietary restrictions. In contrast, novel oral anticoagulants (NOACs), including rivaroxaban, apixaban, and dabigatran, offer improved safety profiles, predictable pharmacokinetics, and fewer interactions. The article emphasizes the importance of individualized patient care when choosing the appropriate anticoagulant therapy and outlines current clinical guidelines and research findings related to anticoagulation management.