Preparation And Characterization of Microencapsulating Drug Delivery Systems of Few Anti-Hypertensive Drugs

The present study focuses on the preparation and characterization of microencapsulated drug delivery systems for selected antihypertensive agents. Microencapsulation is an advanced drug delivery approach that enhances the pharmacokinetic profile, stability, and controlled release of therapeutic agents. In this project, various antihypertensive drugs—such as amlodipine, atenolol, and enalapril cellulose and sodium alginate via techniques such as solvent evaporation and ionic gelation. The goal of developing microencapsulating drug delivery systems (DDS) for antihypertensive treatments is to improve the medications'-controlled release, therapeutic efficacy, and decreased adverse effects. The synthesis and characterization of microencapsulated formulations for a number of widely used antihypertensive medications were examined in this work. Coacervation, solvent evaporation, and spray-drying were among the techniques used in the microencapsulation process to attain the best possible encapsulation efficiency and regulated drug release profiles.