Formulation Of an Epidermal Cream with Collagen Extracted from Cynoglossus Semilaevis Fish Skin

Collagen is the most abundant protein in the human body and also the key structural component of skin, bones, muscles, tendons, ligaments and connective tissue. It provides elasticity, strength and support to various body parts. There are various natural sources for collagen and for this project, marine collagen is used. Marine collagen ha sits unique properties and excellent invitro biodegradability and biocompatibility, making it ideal to repair tissue. This project develops an epidermal cream using collagen extracted from Tongue sole fish (Cynoglossus semilaevis), combined with beeswax and shea butter .Beeswax and shea butter has very good moisturizing effect, anti-inflammatory, act as a natural preservative and also biodegradableThe formulated cream was evaluated for physiochemical properties , showing a ph from 3.3 decreased to 3.0 on the 14th day and viscosities of 129.85Pa.s(brown skin) and 206.04Pa.s (white skin).Stability test confirmed no phase separation , with easy washability.The cream enhances skin hydration,improves skin tone and reduces wrinkles,making it a promising anti-aging formulation.