A Comprehensive Review on Langya Henipavirus (Layv): A New Zoonotic Threat

Langya henipavirus (Lay V) is an emerging zoonotic pathogen belonging to the Henipavirus genus, closely related to the highly pathogenic Nipah and Hendra viruses. First detected in eastern China in 2022, Lay V has raised global concern due to its ability to cross species barriers and its potential public health impact. Although human-to-human transmission has not yet been documented, its genetic resemblance to other high-fatality henipaviruses necessitates close monitoring. This review provides a detailed account of Lay V’s origin, virological properties, clinical manifestations, modes of transmission, and current therapeutic approaches. It also emphasizes the expanding role of pharmacists in areas such as disease surveillance, public education, and outbreak preparedness. In light of the ongoing emergence of zoonotic diseases, Lay V serves as a reminder of the urgent need for integrated healthcare strategies and multidisciplinary readiness.