Cross- Sectional Study on Clinical and Laboratory Profile of the Tuberculosis Patient Admitted in a Tuberculosis Hospital in Tamil Nadu

Introduction: COVID -19 pandemic had a significant impact on both mortality and morbidity of many diseases with no exception on Tuberculosis. This study was done to describe the clinical and laboratory profile of tuberculosis patient and to estimate the prevalence of malnutrition. Materials and Methods: The cross-sectional study was done in the TB hospital attached to the tertiary care hospital, in Madurai among all 226 TB patients admitted during March-May 2024. Data on clinical and laboratory profile was collected using predesigned semi-structured questionnaire. Data analysis done using SPSS and descriptive statistics was used. Results: Among 226 TB patients 78% of them did not have any co-morbidity. Most common comorbidity was Diabetes seen in 15%, 5.8% were reactive for HIV. Smokers and alcoholics were 55.3% and 63.3% respectively. 93.4% were severely malnourished and 94.2% of their BMI fell into underweight category. For 57.5% of the individuals haemoglobin was more than 10g/dl and 97.8% of them had normal temperature. 62.8% and 58% had urea and creatinine within the normal range respectively. Nearly 84% of them had abnormal WBC total count. Majority of them had respiratory rate 18-24 per min (62.8%) and Spo2 >93% (84.1%). Mean TN-KET score was 6.8. Extra pulmonary TB was among 3.9% and 5.3% had drug resistant TB. Conclusion: TB is more prevalent among male population, 40-50 years age group. Infection leads to other secondary problems like anaemia and malnutrition and most common co-morbidity associated is Diabetes.