Correlation of Prolactin Level and Hypothyroidism in both Primary and Secondary Infertility in Females of North Karnataka Population

Background: Infertility in females is one of the major problems in developing countries. The hormones like TSH and prolactin play vital roles in reproduction and sexual life. The abnormal secretion of these hormones leads to infertility in females. Method: 45 primary and 45 secondary infertile women were studied. Complete hemogram, USG abdomen and pelvis and HSG were done. The thyroid function test and prolactin hormone were studied using the Beckman-Coulter Access-II method in every patient. Age distribution and hormone levels in both the primary and secondary groups in fertility were compared. Results: Prolactin hormone levels were 0-20 ng/ml in 19 (42.2%) in group A and 28 (62.2%) in group B, and 21-100 ng/ml in 26 (57.8%) and 16 (35.6%) in group B. >100 ng/ml was zero in group A and 1 (2.2%) in group B. In TSH study, < 0.4mIU/ml in 4 (8.9%) in group A and 3 (6.7%) in group B; 0.4-4.7mIU/ml in 31 (68.9%) in group A and 37 (82.2%) in group B; > 4.7mIU/ml in 10 (22.2%) in group A and 5 (11.1%) in group B. Conclusion: It is observed that, variations in TSH and prolactin hormones leads to infertility in females.