A Case Report on Coagulopathy Induced Pharyngeal and Laryngeal Hematoma

Coagulopathy-induced laryngeal and pharyngeal hematomas represent a rare but potentially life-threatening clinical entity characterized by haemorrhagic infiltration of upper airway soft tissues due to impaired coagulation. These hematomas can result from anticoagulant therapy, thrombocytopenia, inherited bleeding disorders, or systemic conditions such as liver disease or disseminated intravascular coagulation. A 73-year-old female had presented with swelling in the neck and hand and was diagnosed with coagulopathy-induced pharyngeal and laryngeal hematoma. Imaging had revealed hematomas in the tonsillar and laryngeal regions, along with thyroid nodules and thickened aryepiglottic folds. Laboratory tests had shown dimorphic anemia, elevated INR, and increased CRP, suggesting underlying inflammation and coagulopathy. She had been managed with FFP transfusion, supportive care, antibiotics, vitamin K, tranexamic acid, and other symptomatic medications, and ENT evaluation later confirmed hematoma resolution with subsequent adjustment of her treatment plan. Early recognition and multidisciplinary management are essential to prevent morbidity and mortality. This condition underscores the importance of careful monitoring in patients with bleeding diatheses or on anticoagulation, particularly when presenting with upper airway symptoms.