Epilepsy Care in India: A Review of Recent Therapeutic Advances

In India, there are about 10 million people with epilepsy (PWE). Despite the availability of antiepileptic medications (AEDs), PWE have a significant treatment gap that ranges from 50 to 70%. Poor education, poverty, cultural beliefs, stigma, and inadequate healthcare infrastructure are the causes of this gap for curable epilepsy, while improper diagnosis and treatment are the causes of this gap for chronic epilepsy. Researchers from all across the world have made remarkable strides in the prevention, treatment, and cure of epilepsy. Significant advancements have also been made in Indian research, but the majority of these studies concentrate on the genetic correlations, epidemiological aspects of epilepsy, identification, and validation of novel AEDs in animal models of the condition.The dynamic process of epileptogenesis, in which neurons start to exhibit aberrant firing patterns that result in epileptic seizures, has been the subject of very few investigations. While studies on resected brain tissues from epilepsy patients are clinically useful, in-depth research can be done using animal epilepsy models. Lastly, to improve the caliber of epilepsy research in India, further financial assistance from the government and partnerships between basic research institutes, medical institutes, and companies are needed.The assessment of the present state of epilepsy research in India and the necessity of identifying viable anti-epileptogenic treatments are the main objectives of this review.