CLINICAL AND IMMUNOLOGICAL ASPECTS OF PROGNOSIS AND PREVENTION OF GENERALIZATION OF INFECTION IN PATIENTS WITH CHRONIC WOUNDS

The article deals with clinical and immunological aspects of prognosis and prevention of generalization of infection in patients with chronic non-healing wounds. Risk factors for infectious complications, mechanisms of inflammation, and features of the immune response in the context of long-term wound healing are discussed. Methods for diagnosing and monitoring the state of the immune system, as well as the principles of treatment and prevention of infection, including the use of antibacterial and immunomodulatory drugs, are described. Recommendations for optimizing approaches in the treatment and prevention of generalization of infection are proposed.