Studies on evaluation of Lipid Profile and Cardiac Biomarkers of Hospital Population

Coronary Artery Diseases (CAD) represent a significant global health burden, predominantly affecting middle-aged populations as reported by WHO. This study aims to evaluate comprehensive biochemical parameters and cardiac marker enzymes in patients presenting with severe cardiac complications. In this cross-sectional study, fasting blood samples were collected from 200 confirmed cardiac patients (n=200; comprising both males and females) and analysed following standardized laboratory protocols using ERBA diagnostic kits. Patients were stratified based on age and gender for detailed analysis. Results demonstrated significantly elevated lipid profiles with Total Cholesterol (320 mg/dl), Triglycerides (270 mg/dl), and LDL-Cholesterol (240 mg/dl), accompanied by consistently decreased HDL-Cholesterol levels (<30mg/dl) across all age groups. Analysis of cardiac biomarker enzymes revealed marked elevation in SGOT (>130 IU), SGPT (>135 IU), GGT (>131 IU), and ALP (>207 IU) levels. These findings indicate a significant comorbidity between CAD and hepatic dysfunction. This comprehensive investigation establishes a clear correlation between elevated lipid profiles, altered cardiac markers, and increased cardiac risk. The study concludes that intensive lifestyle modifications and dietary interventions are crucial for these patients, emphasizing the need for a holistic treatment approach combining cardiac and hepatic care.