Atypical Metastasis of Endometrial Cancer, Case Report

Endometrial cancer is the most common malignancy of the female reproductive system, with increasing incidence rates. While pelvic lymph node metastases occur in approximately 21% of cases, cutaneous metastases are rare, representing only 0.8% of instances. This case report describes a 40-year-old female patient with a soft tissue tumor in the right thigh, initially suspected of having metastatic endometrial carcinoma. The patient had a history of dysmenorrhea and hypermenorrhea, and presented with a progressively enlarging lesion. Imaging revealed a hypoechoic mass with vascular characteristics, leading to an incisional biopsy. Pathological analysis indicated malignant neoplastic tissue suggestive of genitourinary origin, likely endometrial. This case underscores the rarity of cutaneous metastases from endometrial adenocarcinoma and highlights the importance of considering internal malignancies in patients with unusual skin lesions.