Astrocyte-Glycogen Maps as Surface Storage Patterns

This work proposes a unified interpretation of glycogen metabolism in astrocytes as part of a broader gauge-field-based systemic geometry. Rather than treating astrocytes as passive supporters of neural activity, we characterize them as metabolic gatekeepers and dynamic surface-phase managers—functionally analogous to the liver within the nervous system. The study introduces the concept of gauge coupling between cellular membranes and mitochondrial surfaces, where phase gradients (∂φ/∂x, ∂φ/∂t) govern energy distribution, signaling, and feedback regulation. These φ-mediated interactions form closed-loop interference circuits, maintaining physiological coherence across scales. Extending this framework, we show that biological circuits, electrical networks, and socioeconomic systems all derive stability from self-closing gauge loops. When such loops are severed—whether in the brain, in metabolism, or in finance—degenerate zones (analogous to black holes or economic bubbles) arise as collapsed symmetry fields. Paradoxically, such collapses may also seed new gauge structures, initiating cycles of re-symmetrization. Through this lens, phenomena ranging from sleep pressure to financial instability are reinterpreted as expressions of φ-field dynamics and gauge connectivity across hierarchical membranes.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-08-04
DOI
https://doi.org/10.5281/zenodo.16735130
Primary Topic
Neuroscience and Neuropharmacology Research
Type
article
Field-Weighted Citation Impact
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article

Astrocyte-Glycogen Maps as Surface Storage Patterns

Zenodo (CERN European Organization for Nuclear Research)
Neuroscience and Neuropharmacology Research
article

Astrocyte-Glycogen Maps as Surface Storage Patterns

article en

Abstract

This work proposes a unified interpretation of glycogen metabolism in astrocytes as part of a broader gauge-field-based systemic geometry. Rather than treating astrocytes as passive supporters of neural activity, we characterize them as metabolic gatekeepers and dynamic surface-phase managers—functionally analogous to the liver within the nervous system. The study introduces the concept of gauge coupling between cellular membranes and mitochondrial surfaces, where phase gradients (∂φ/∂x, ∂φ/∂t) govern energy distribution, signaling, and feedback regulation. These φ-mediated interactions form closed-loop interference circuits, maintaining physiological coherence across scales. Extending this framework, we show that biological circuits, electrical networks, and socioeconomic systems all derive stability from self-closing gauge loops. When such loops are severed—whether in the brain, in metabolism, or in finance—degenerate zones (analogous to black holes or economic bubbles) arise as collapsed symmetry fields. Paradoxically, such collapses may also seed new gauge structures, initiating cycles of re-symmetrization. Through this lens, phenomena ranging from sleep pressure to financial instability are reinterpreted as expressions of φ-field dynamics and gauge connectivity across hierarchical membranes.

Zenodo (CERN European Organization for Nuclear Research)
Kappa Omicron Nu Honor Society (US)
Openalex Percentile: Top 49%
Neuroscience and Neuropharmacology Research
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