A Review on Gastro Retentive Drug Delivery System (GRDDS)

The gastroretentive Drug Delivery System (GRDDS) is a novel method of oral medication administration that tackles significant issues with traditional systems. way to take drugs since it is convenient, patient-compliant, and flexible. Traditional oral drug delivery techniques, however, frequently encounter gastrointestinal (GI) tract restrictions, including insufficient drug release, diminished efficacy, and the requirement for frequent dosing. In order to address these issues, GRDDS extends the gastric residence time (GRT) of medications, allowing them to remain in the stomach for a longer period of time. By providing controlled, sustained drug release, improving drug absorption, and improving targeted distribution within the stomach, this extended GRT increases therapeutic efficacy and lowers the frequency of dose. This review examines the fundamentals, varieties, and advantages of GRDDS, highlighting how it can optimize drug release, boost bioavailability, and enhance overall therapy results.