TO EVALUATE THE EFFECTIVENESS OF HPV ELIMINATION WHEN USING RECOMBINANT INTERFERON

TO EVALUATE THE EFFECTIVENESS OF HPV ELIMINATION WHEN USING RECOMBINANT INTERFERON Utayev Akbar Juraqulovich Chief physician of the regional branch of the Republican Specialized Dermatovenerology and Cosmetology Scientific and Applied Medical Center of Samarkand Region https://doi.org/10.5281/zenodo.14660052 Abstract: The task set before us for writing this article was to evaluate the effectiveness of HPV elimination using recombinant interferon alpha-2b in patients with positive HPV tests and no clinical manifestations of infection. To achieve our goals and objectives, we analyzed samples of scraping material from the urethra in men and the cervical canal of women who applied for an appointment at the Dermatovenereology Center. DNA was isolated from the resulting material for subsequent real-time PCR testing for the presence of HPV types 6, 11, 31, 33, 51, 52, 56, 16, 18. As a result, we came to the conclusion that the applied algorithm for managing patients with positive screening tests for HPV and the absence of clinical manifestations of infection showed encouraging results, since in the majority of those examined, HPV disappeared after therapy in an unusually short time. For a more in-depth assessment of the effectiveness of the proposed algorithm, it is necessary to conduct further research in this direction with the involvement of a larger cohort of patients and the formation of a control group. Key words: Alpha -2b, HPV, PCR, DNA, effectiveness, interferon, algorithm, patients, recombinant interferon, analyzed.