To Assess the Levels of Serum Uric Acid in Hypertensive Retinopathy

Introduction: One of the microvascular side effects of hypertension that develops gradually is hypertensive retinopathy (HR). Gout is predisposed to by hyperuricemia, which is associated with metabolic syndrome. Additionally, it was considered a stand-alone risk factor for hypertension. SUA may be linked to certain eye conditions, according to a number of studies. The purpose of this study is to highlight how metabolic parameters affect heart rate, and it is hypothesized that SUA gave doctors valuable information about when to perform fundoscopic exams on hypertensive patients. Aim: To study the serum uric acid concentration (SUA) in patients of hypertensive retinopathy and relationship between both. Methodology: Observational cross sectional study was conducted to observe the relationship between serum uric acid and hypertensive retinopathy. Two groups cases 120 (with HR) and controls 120 (without HR) were compared. Serum uric acid was measured by Erba Mannheim XL 640 machine at MBS Hospital Kota. Hypertensive Retinopathy was assessed using indirect ophthalmoscope. Results & Conclusion: The data analysis of the cases showed the mean SUA level to be 6.2398(mg/dl) and the controls showed the mean SUA level of 5.5926(mg/dl). A two sample t-Test to compare the means of Serum Uric Acid Level (mg/dl) for Cases and Controls. Significance value (p value) for the test was achieved 0.015 (significant). Thus the study conclude that serum uric acid level is associated with incidence of Hypertensive Retinopathy. And according to ANOVA test it was also found that serum uric acid is associated with severity of Hypertensive Retinopathy. It was hypothesized that SUA gave doctors helpful information for scheduling funduscopic exams in hypertension patients and highlighted the impact of metabolic variables on HR.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-12-30
DOI
https://doi.org/10.5281/zenodo.14619826
Primary Topic
Gout, Hyperuricemia, Uric Acid
Type
article
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article

To Assess the Levels of Serum Uric Acid in Hypertensive Retinopathy

Zenodo (CERN European Organization for Nuclear Research)
Gout, Hyperuricemia, Uric Acid
article

To Assess the Levels of Serum Uric Acid in Hypertensive Retinopathy

article en

Abstract

Introduction: One of the microvascular side effects of hypertension that develops gradually is hypertensive retinopathy (HR). Gout is predisposed to by hyperuricemia, which is associated with metabolic syndrome. Additionally, it was considered a stand-alone risk factor for hypertension. SUA may be linked to certain eye conditions, according to a number of studies. The purpose of this study is to highlight how metabolic parameters affect heart rate, and it is hypothesized that SUA gave doctors valuable information about when to perform fundoscopic exams on hypertensive patients. Aim: To study the serum uric acid concentration (SUA) in patients of hypertensive retinopathy and relationship between both. Methodology: Observational cross sectional study was conducted to observe the relationship between serum uric acid and hypertensive retinopathy. Two groups cases 120 (with HR) and controls 120 (without HR) were compared. Serum uric acid was measured by Erba Mannheim XL 640 machine at MBS Hospital Kota. Hypertensive Retinopathy was assessed using indirect ophthalmoscope. Results & Conclusion: The data analysis of the cases showed the mean SUA level to be 6.2398(mg/dl) and the controls showed the mean SUA level of 5.5926(mg/dl). A two sample t-Test to compare the means of Serum Uric Acid Level (mg/dl) for Cases and Controls. Significance value (p value) for the test was achieved 0.015 (significant). Thus the study conclude that serum uric acid level is associated with incidence of Hypertensive Retinopathy. And according to ANOVA test it was also found that serum uric acid is associated with severity of Hypertensive Retinopathy. It was hypothesized that SUA gave doctors helpful information for scheduling funduscopic exams in hypertension patients and highlighted the impact of metabolic variables on HR.

Zenodo (CERN European Organization for Nuclear Research)
Government Medical College (IN)
Good health and well-being
Openalex Percentile: Top 50%
Gout, Hyperuricemia, Uric Acid
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To Assess the Levels of Serum Uric Acid in Hypertensive Retinopathy · Zenodo (CERN European Organization for Nuclear Research) (2024) | TGRS Research Map | TGRS