Hidradenocarcinoma a rare case and challenging diagnosis

ABSTRACT: Hidradenocarcinoma is a rare malignant adnexal tumor arising from eccrine sweat glands, with diagnostic and therapeutic challenges due to its benign clinical appearance and limited literature on standardized management. We report the case of a 66-year-old male who presented with a painless, progressively enlarging axillary swelling initially suspected to be hidradenitis suppurativa. Surgical excision followed by histopathological and immunohistochemical evaluation confirmed the diagnosis of hidradenocarcinoma. This case underscores the importance of considering a broad differential diagnosis when evaluating atypical cutaneous lesions, as they may be malignant despite appearing benign. Through this report, we aim to contribute to the limited literature on hidradenocarcinoma and support the development of more effective management strategies for this rare condition. Keywords: Hidradenoma, Hidradenitis Suppurative, Sweat Gland Neoplasm, Hidradenocarcinoma

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-01
DOI
https://doi.org/10.5281/zenodo.15305873
Primary Topic
Cancer and Skin Lesions
Type
article
Field-Weighted Citation Impact
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article

Hidradenocarcinoma a rare case and challenging diagnosis

Zenodo (CERN European Organization for Nuclear Research)
Cancer and Skin Lesions
article

Hidradenocarcinoma a rare case and challenging diagnosis

article en

Abstract

ABSTRACT: Hidradenocarcinoma is a rare malignant adnexal tumor arising from eccrine sweat glands, with diagnostic and therapeutic challenges due to its benign clinical appearance and limited literature on standardized management. We report the case of a 66-year-old male who presented with a painless, progressively enlarging axillary swelling initially suspected to be hidradenitis suppurativa. Surgical excision followed by histopathological and immunohistochemical evaluation confirmed the diagnosis of hidradenocarcinoma. This case underscores the importance of considering a broad differential diagnosis when evaluating atypical cutaneous lesions, as they may be malignant despite appearing benign. Through this report, we aim to contribute to the limited literature on hidradenocarcinoma and support the development of more effective management strategies for this rare condition. Keywords: Hidradenoma, Hidradenitis Suppurative, Sweat Gland Neoplasm, Hidradenocarcinoma

Zenodo (CERN European Organization for Nuclear Research)
Christian Medical College, Vellore (IN), Christian Medical College (IN)
Good health and well-being
Openalex Percentile: Top 33%
Cancer and Skin Lesions
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Hidradenocarcinoma a rare case and challenging diagnosis · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS