Infertility in Women of Reproductive Age: Association of Thyroid Hormones with FSH, LH, and Prolactin

Background: The estimated prevalence of infertility ranges from 12 to 14 percent. Thus, it is a prevalent ailment with significant psychological, physical, and financial ramifications. In order to properly assess these illnesses, a multifaceted diagnostic strategy is required. Thyroid hormones, FSH, LH, and prolactin were correlated with infertility in women of reproductive age in this present study. Aim of this study was to correlate thyroid hormones with FSH, LH and prolactin in infertility in the reproductive age group women. Methods: Between the ages of 19 and 45, a total of 60 infertile women and 40 healthy, fertile women volunteers were chosen based on OPD. Twenty of the 60 infertile women had secondary infertility, while 40 had original infertility. They underwent Chemiluminescence Immunoassay (CLIA) to check their thyroid hormone levels. Result: There was a positive correlation between TSH and prolactin. Additionally, they had a negative correlation with T3, FSH, and LH in infertile groups. Thus, we can conclude that hypothyroidism and hyperprolactinemia are important factors in the etiopathogenesis of infertility. Chronic hypothyroidism can lead to hyperprolactinemia and ovulatory dysfunction. Conclusion: Therefore, it may be very beneficial to detect and treat hypothyroidism early on, before ovulatory dysfunction and hyperprolactinemia manifest. In order to identify subclinical thyroid issues and reduce the risk of infertility, TSH screening should be performed on all women in the early reproductive age range.