The Role of the Vaginal Microbiome in Women's Reproductive Health

The vaginal microbiome plays a fundamental role in maintaining women’s reproductive health. A balanced microbiota, primarily dominated by Lactobacillus species, provides protection against infections, regulates vaginal pH, and supports fertility. However, dysbiosis—a disruption in microbial balance—can lead to bacterial vaginosis (BV), yeast infections, sexually transmitted infections (STIs), and even pregnancy complications. This article explores the composition of the vaginal microbiome, its interaction with the immune system, and its impact on gynecological and obstetric health. Emerging treatments, including probiotics and microbiome-targeted therapies, are also discussed.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-02-14
DOI
https://doi.org/10.5281/zenodo.14871280
Primary Topic
Reproductive tract infections research
Type
article
Field-Weighted Citation Impact
0.00
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article

The Role of the Vaginal Microbiome in Women's Reproductive Health

Zenodo (CERN European Organization for Nuclear Research)
Reproductive tract infections research
article

The Role of the Vaginal Microbiome in Women's Reproductive Health

article en

Abstract

The vaginal microbiome plays a fundamental role in maintaining women’s reproductive health. A balanced microbiota, primarily dominated by Lactobacillus species, provides protection against infections, regulates vaginal pH, and supports fertility. However, dysbiosis—a disruption in microbial balance—can lead to bacterial vaginosis (BV), yeast infections, sexually transmitted infections (STIs), and even pregnancy complications. This article explores the composition of the vaginal microbiome, its interaction with the immune system, and its impact on gynecological and obstetric health. Emerging treatments, including probiotics and microbiome-targeted therapies, are also discussed.

Zenodo (CERN European Organization for Nuclear Research)
Wuhan No.1 Hospital (CN), Yaroslavl State Technical University (RU)
Gender equality
Openalex Percentile: Top 51%
Reproductive tract infections research
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