An Occurrence of Transverse Myelitis in Systemic Lupus Erythematosus: A Case Study

Introduction Lupus myelitis is a rare but severe neurological complication of systemic lupus erythematosus (SLE), a complex autoimmune disorder affecting multiple organ systems. Neurological manifestations are common in SLE, occurring in up to 60% of patients, typically presenting as cerebrovascular events, seizures, or peripheral neuropathy. However, lupus myelitis, a condition involving spinal cord inflammation, is an exceedingly rare occurrence, reported in only 1–2% of SLE cases. It often manifests as transverse myelitis, which can be complete or partial, impacting sensory and motor functions. The resulting disability can significantly impair a patient’s quality of life, making it one of the most debilitating complications of SLE. Despite its rarity, lupus myelitis poses substantial diagnostic and therapeutic challenges due to its overlap with other neurological conditions and aggressive clinical course. Early recognition and intervention are essential to minimize irreversible damage. This report highlights the case of an 11-year-old girl with lupus myelitis, illustrating the complexity of diagnosis and management in this rare condition and the systemic nature of SLE in pediatric patients.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-12-01
DOI
https://doi.org/10.5281/zenodo.14257668
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
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article

An Occurrence of Transverse Myelitis in Systemic Lupus Erythematosus: A Case Study

Zenodo (CERN European Organization for Nuclear Research)
Systemic Lupus Erythematosus Research
article

An Occurrence of Transverse Myelitis in Systemic Lupus Erythematosus: A Case Study

article en

Abstract

Introduction Lupus myelitis is a rare but severe neurological complication of systemic lupus erythematosus (SLE), a complex autoimmune disorder affecting multiple organ systems. Neurological manifestations are common in SLE, occurring in up to 60% of patients, typically presenting as cerebrovascular events, seizures, or peripheral neuropathy. However, lupus myelitis, a condition involving spinal cord inflammation, is an exceedingly rare occurrence, reported in only 1–2% of SLE cases. It often manifests as transverse myelitis, which can be complete or partial, impacting sensory and motor functions. The resulting disability can significantly impair a patient’s quality of life, making it one of the most debilitating complications of SLE. Despite its rarity, lupus myelitis poses substantial diagnostic and therapeutic challenges due to its overlap with other neurological conditions and aggressive clinical course. Early recognition and intervention are essential to minimize irreversible damage. This report highlights the case of an 11-year-old girl with lupus myelitis, illustrating the complexity of diagnosis and management in this rare condition and the systemic nature of SLE in pediatric patients.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 46%
Systemic Lupus Erythematosus Research
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