Case Report: A Rare Case of Cerebellar Gliosarcoma

Gliosarcoma is a rare subtype of glioblastoma multiforme. On histology it is a biphasic tumor having both glial as well as sarcomatous components. Here in we present a case of 32 year male who got admitted to our hospital with chief complaints of headache for the past one month which increased in intensity since the last 10 days with progressive loss of vision and complaints of giddiness, nausea and vomiting. CT scan and MRI were advised which revealed Approximately 47x40x28mm sized ill-defined heterogeneous lesion in the right cerebellar hemisphere causing mass effect over fourth ventricle. A provisional diagnosis of medullobastoma was made based on imaging studies. Surgical intervention comprising Midline suboccipital craniotomy with excision of tumor was done. On histopathological examination a diagnosis of gliosarcoma was made after observing the H&E and Reticulin silver stained sections. Gliosarcoma is an aggressive tumor hence prompt and accurate diagnosis is required for better prognosis.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-10-26
DOI
https://doi.org/10.5281/zenodo.14247019
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Case Report: A Rare Case of Cerebellar Gliosarcoma

Zenodo (CERN European Organization for Nuclear Research)
Glioma Diagnosis and Treatment
article

Case Report: A Rare Case of Cerebellar Gliosarcoma

article en

Abstract

Gliosarcoma is a rare subtype of glioblastoma multiforme. On histology it is a biphasic tumor having both glial as well as sarcomatous components. Here in we present a case of 32 year male who got admitted to our hospital with chief complaints of headache for the past one month which increased in intensity since the last 10 days with progressive loss of vision and complaints of giddiness, nausea and vomiting. CT scan and MRI were advised which revealed Approximately 47x40x28mm sized ill-defined heterogeneous lesion in the right cerebellar hemisphere causing mass effect over fourth ventricle. A provisional diagnosis of medullobastoma was made based on imaging studies. Surgical intervention comprising Midline suboccipital craniotomy with excision of tumor was done. On histopathological examination a diagnosis of gliosarcoma was made after observing the H&E and Reticulin silver stained sections. Gliosarcoma is an aggressive tumor hence prompt and accurate diagnosis is required for better prognosis.

Zenodo (CERN European Organization for Nuclear Research)
Sardar Patel Medical College (IN)
Good health and well-being
Openalex Percentile: Top 45%
Glioma Diagnosis and Treatment
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