Hybrid Deep Learning Framework for Interpretable Healthcare Diagnostics: Integrating Multi-Modal Data for Enhanced Trust and Accuracy

The growing use of artificial intelligence (AI) within healthcare demands models that boast both high-performance and interpretability. This study presents a hybrid deep learning framework that combines multi-modal data for precise disease predictions along with actionable and interpretable insights, which in turn can drastically enhance the quality of diagnosis. Through the integration of CNN and Transformer-based models, along with advanced feature fusion techniques, the comprehensive framework guarantees those whose predictive performance is optimal across a wide range of datasets. Additionally, employ explainability modules like Grad-CAM, SHAP which allows users to see why the model made a certain prediction with visualizations in a more interpretable manner like heatmaps or feature importance scores, thus increasing trust in the model. Experiments on public datasets (e.g., MIMIC-IV, ChestX-ray8, and COVID-19 CT) show better accuracy and higher explainability than traditional black-box models. This study forges a vital connection in the space of healthcare AI, stressing the importance of performance along with transparency to support the ethical and effective implementation of AI systems in the clinical environment.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-03-23
DOI
https://doi.org/10.5281/zenodo.15069851
Primary Topic
Explainable Artificial Intelligence (XAI)
Type
article
Field-Weighted Citation Impact
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article

Hybrid Deep Learning Framework for Interpretable Healthcare Diagnostics: Integrating Multi-Modal Data for Enhanced Trust and Accuracy

Zenodo (CERN European Organization for Nuclear Research)
Explainable Artificial Intelligence (XAI)
article

Hybrid Deep Learning Framework for Interpretable Healthcare Diagnostics: Integrating Multi-Modal Data for Enhanced Trust and Accuracy

article en

Abstract

The growing use of artificial intelligence (AI) within healthcare demands models that boast both high-performance and interpretability. This study presents a hybrid deep learning framework that combines multi-modal data for precise disease predictions along with actionable and interpretable insights, which in turn can drastically enhance the quality of diagnosis. Through the integration of CNN and Transformer-based models, along with advanced feature fusion techniques, the comprehensive framework guarantees those whose predictive performance is optimal across a wide range of datasets. Additionally, employ explainability modules like Grad-CAM, SHAP which allows users to see why the model made a certain prediction with visualizations in a more interpretable manner like heatmaps or feature importance scores, thus increasing trust in the model. Experiments on public datasets (e.g., MIMIC-IV, ChestX-ray8, and COVID-19 CT) show better accuracy and higher explainability than traditional black-box models. This study forges a vital connection in the space of healthcare AI, stressing the importance of performance along with transparency to support the ethical and effective implementation of AI systems in the clinical environment.

Zenodo (CERN European Organization for Nuclear Research)
Gachon University (KR), Riphah International University (PK), Al-Buraimi University College (OM), University of Buraimi (OM)
Openalex Percentile: Top 75%
Explainable Artificial Intelligence (XAI)
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Hybrid Deep Learning Framework for Interpretable Healthcare Diagnostics: Integrating Multi-Modal Data for Enhanced Trust and Accuracy · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS