"Neonatal RBC Dynamics and Skin Signaling: Novel Pathway to Early Hepatic Stellate Cell Activation"

This document presents a novel hypothesis linking neonatal red blood cell dynamics, perinatal stress, bile homeostasis, and skin-derived signaling to early hepatic stellate cell activation and potential liver fibrosis later in life. The text includes a causal chain model, discussion of underlying mechanisms, and references. It is intended as a scientific innovation record.