Effect of Aflatoxin Contaminated Diet on Male Reproductive Organ of Rabbits

Abstract Aflaxtoxins are secondary toxic fungal metabolites produced by Aspergillus flavus. Ingestion of aflatoxin contaminated food / feed stuffs cause occurrence of a serious toxic disease called aflatoxicosis. Reduction in glycogen ( P<0.02) and protein contents (P <0.05). were followed with elevation in lipid ( P< 0.001 ) while sodium, Potassium, magnesium and inorganic Phosphorus contents reduced, calcium concentration was increased in the testis of aflatoxic rabbits. Percent ash content increased in aflatoxin fed rabbits indicating accumulation of inorganic constituents. Among monovalent cations, sodium concentration was comparatively higher than potassium (Na+/K+ = 1.62). Ingestion of aflatoxin contaminated diet for 90 days caused increase in sodium and reduction in potassium contents, as a result the ratio between sodium and potassium was increased (2.78). Some of the key enzyme activities were estimated 1n testis of rabbits during aflatoxicosis. Activity of SDH showed a decrease suggesting decreased operation of mitochondrial TCA cycle. LDH and G-5-pase activities showed significant increase (P < 0.00l).Some of the key enzyme activities were estimated in testis of rabbits during aflatoxicosis. Activities of Acpase. Alkpase. LDH and G-6-pase significantly increased while SDH activity was significantly decreased.