Acute Liver Failure Complicating Pregnancy: A Multidisciplinary Approach to Management

Acute liver failure (ALF) during pregnancy is a rare but life-threatening condition associated with high maternal and fetal morbidity and mortality. We present a case of a 22-year-old primigravida at 30 weeks gestation who developed ALF with concurrent HELLP syndrome, disseminated intravascular coagulation (DIC), acute kidney injury (AKI), and posterior reversible encephalopathy syndrome (PRES). Despite the complexity of the presentation, a multidisciplinary team comprising obstetricians, intensivist, hepatologist, nephrologist, and neurologist collaborated to provide timely and comprehensive management. This case underscores the importance of a coordinated approach to optimize maternal and neonatal outcomes in such challenging scenarios.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-09-26
DOI
https://doi.org/10.5281/zenodo.14468559
Primary Topic
Liver Disease and Transplantation
Type
article
Field-Weighted Citation Impact
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article

Acute Liver Failure Complicating Pregnancy: A Multidisciplinary Approach to Management

Zenodo (CERN European Organization for Nuclear Research)
Liver Disease and Transplantation
article

Acute Liver Failure Complicating Pregnancy: A Multidisciplinary Approach to Management

article en

Abstract

Acute liver failure (ALF) during pregnancy is a rare but life-threatening condition associated with high maternal and fetal morbidity and mortality. We present a case of a 22-year-old primigravida at 30 weeks gestation who developed ALF with concurrent HELLP syndrome, disseminated intravascular coagulation (DIC), acute kidney injury (AKI), and posterior reversible encephalopathy syndrome (PRES). Despite the complexity of the presentation, a multidisciplinary team comprising obstetricians, intensivist, hepatologist, nephrologist, and neurologist collaborated to provide timely and comprehensive management. This case underscores the importance of a coordinated approach to optimize maternal and neonatal outcomes in such challenging scenarios.

Zenodo (CERN European Organization for Nuclear Research)
Sir Sayajirao General Hospital Medical College (IN), Indian Institute of Information Technology Vadodara (IN), Nephrology Center of Maryland (US), KM Shah Dental College and Hospital (IN), Defense & Veterans Center for Integrative Pain Management (US)
Good health and well-being
Openalex Percentile: Top 50%
Liver Disease and Transplantation
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