Wide Local Excision for Dermatofibrosarcoma Protuberans: A Surgical Approach

Introduction: Darier and Ferrand dermatofibrosarcoma is a locally malignant soft-tissue sarcoma with a high recurrence rate and rare metastasis, first described in 1924. Results: This retrospective study analyzes 20 cases of chest wall dermatofibrosarcoma treated at Hassan II University Hospital in Fez from 2009 to 2023. The median patient age was 44.95 years, with a slight female predominance. Tumors varied in size and presentation, commonly appearing as multi-nodular or ulcerating masses. Histological analysis showed spindle-shaped cells with CD34 expression. Surgical treatment involved wide excision with a 5 cm safety margin, followed by reconstruction using skin grafting or directed healing. Conclusion: Over an average follow-up of 23 months, no recurrences were observed, highlighting the importance of early diagnosis and multidisciplinary management to improve outcomes and minimize the need for complex surgical repairs.

Institutions

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-14
DOI
https://doi.org/10.5281/zenodo.15412771
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Wide Local Excision for Dermatofibrosarcoma Protuberans: A Surgical Approach

Zenodo (CERN European Organization for Nuclear Research)
Sarcoma Diagnosis and Treatment
article

Wide Local Excision for Dermatofibrosarcoma Protuberans: A Surgical Approach

article en

Abstract

Introduction: Darier and Ferrand dermatofibrosarcoma is a locally malignant soft-tissue sarcoma with a high recurrence rate and rare metastasis, first described in 1924. Results: This retrospective study analyzes 20 cases of chest wall dermatofibrosarcoma treated at Hassan II University Hospital in Fez from 2009 to 2023. The median patient age was 44.95 years, with a slight female predominance. Tumors varied in size and presentation, commonly appearing as multi-nodular or ulcerating masses. Histological analysis showed spindle-shaped cells with CD34 expression. Surgical treatment involved wide excision with a 5 cm safety margin, followed by reconstruction using skin grafting or directed healing. Conclusion: Over an average follow-up of 23 months, no recurrences were observed, highlighting the importance of early diagnosis and multidisciplinary management to improve outcomes and minimize the need for complex surgical repairs.

Zenodo (CERN European Organization for Nuclear Research)
Polyclinic Medical Center (US), Centre Hospitalier Universitaire Hassan II (MA), Sidi Mohamed Ben Abdellah University (MA)
Good health and well-being
Openalex Percentile: Top 37%
Sarcoma Diagnosis and Treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.