SPIONs Weapons by Moringa Oleifera finally improves outcome of Multi-Organ Damages (MODs) Prevention: Fact or hype for Reason behind Fighting High Sepsis Rates

Abstract— Introduction: Spinel ferrite nanoparticles (Superparamagnetic Iron Oxide Nanoparticles/SPIONs) semiconductors have been broadly reported to kill bacteria outside the human body. SPIONs as photocatalytic agents in coloring dye water treatment have different mechanisms, it’s a redox reaction. SPIONs as MRI agents have the same principle as bacteria killer, to emit electromagnetic waves. Winning against the high prevalence of MODs and sepsis is the aim of this study. Method: Review article of Ex/Em SPIONs semiconductor in Photothermal Therapy (PTT). Result: Table of 16 references which support SPIONs as New Generation (NG) antibiotic to kill resistant bacteria inside the body. Discussion: Moringa oleifera gold composite NPs vs. NG beta-lactams. SPIONs green synthesis gold composite NPs are used as photothermal therapy (PTT) based on inducing hyperthermia to kill bacteria inside the body: NG MDR eradication. Conclusion: PTT therapy achieved with SPIONs, under NIR, is used to kill MDR, XDR, TDR micro-bacteria, fungi and cancer cells inside the human body.