PHYTOCHEMICAL SCREENING AND GC-MS/MS ANALYSIS OF METHANOLIC EXTRACT OF COLEUS PROSTRATUS

Coleus prostratus commonly known as “Tangled heart plant or Swedish Ivy” belongs to the family Lamiaceae (Labiatae). This study aims to evaluate the plant by phytochemical studies as well as GC-MS analysis of plant extract. Various types of components and bioactive compounds are found in the herbal preparations and the botanicals which provides opportunities for new drug lead. Integrated approach of the study includes plant identification, extraction followed by phytochemical analysis and GC-MS analysis. Biological or pharmacological activity of plant is mainly depended on the components of plant and the amount bioactive compounds as well as primary and secondary metabolites present in it. Microscopic studies of areal parts of plant were also done and which includes transverse section of leaf and stem, longitudinal section of leaf, powder characteristics. The Soxhlet method were used for extraction and then extract were subjected to Gas Chromatography- Mass Spectrophotometer for the characterization of phytocomponents. Total amount of phenolic compounds, alkaloids and flavonoids were also estimated by spectrophotometric method.