Giant-cell Reparative Granuloma of Short Tubular Bones of the Hand.

Abstract: Giant cell reparative granuloma are uncommon reactive intraosseous lesions, with a benign nature and have been reported to occur in the skull, jaw, and facial bones and rarely in tubular bones of hand, feet. They are non-neoplastic solitary, lytic, expansile lesion which rarely may extend into the surrounding soft tissue. It is usually difficult to distinguish them from aneurysmal bone cyst, giant-cell tumor, or brown tumor of hyperparathyroidism due to their radiological and histologic similarities. This report describes two cases of GCRG: a 36-year-old male with a solitary lesion in the metacarpal of the index finger and a 6-year-old female presenting with a similar lesion in the proximal phalanx. Both cases demonstrate the importance of thorough clinical evaluation, imaging, and histopathological examination to achieve an accurate diagnosis. We discuss the surgical management employed in each case and the favorable long-term outcomes observed, underscoring the need for careful differentiation from other bone pathologies.