Superficial Cutaneous Sporotrichosis, Report of a Case with Adequate Response

Introduction: Sporotrichosis is a mycosis caused by the fungus of the genus Sporothrix, of which six species related to human sporotrichosis are recognized, being the S. schenkii complex the most related to transmission in humans. The entry of the agent occurs by contact between the injured skin and the fungal spores, subsequently the fungal conidia are deposited in the host tissue and when introduced, become yeast. The fungus, now in its yeast-like phase, may remain at the site of entry or spread to other sites following the lymphatic vessels (1). Case presentation: We present the case of a 62-year-old male patient with arterial hypertension of 6 years of evolution, gardener, who came to our unit due to the presence of blistering and ulcerative lesions (image 1) on the foot and ipsilateral thigh. He received empirical treatment by private means with acyclovir cream and oxytetracycline, due to the characteristics of the lesions he was treated for herpes zoster with standard dose Acyclovir, he was seen in an outpatient internal medicine clinic one week later. Due to persistence of lesions and scarce reduction in symptomatology, a diagnosis was made according to clinical history, dermal and biochemical pattern of probable mycosis, with emphasis on sporotrichosis or “gardener's disease”, initiating treatment with itraconazole fractional dose for four weeks, with weekly follow-up of the case. Conclusions: At present, the diagnosis of S. schenkii, is of exclusion, in the face of predominant agents in the region. The most frequent clinical forms in humans are the fixed cutaneous form, the lymphatic form and the disseminated form; the latter has a poor prognosis due to its association with immunodeficiencies. Our case is an example of timely diagnosis with appropriate initial azole-based treatment, reflecting a successful case response, inviting the clinician to early integration

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-01-22
DOI
https://doi.org/10.5281/zenodo.14722904
Primary Topic
Fungal Infections and Studies
Type
article
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article

Superficial Cutaneous Sporotrichosis, Report of a Case with Adequate Response

Zenodo (CERN European Organization for Nuclear Research)
Fungal Infections and Studies
article

Superficial Cutaneous Sporotrichosis, Report of a Case with Adequate Response

article en

Abstract

Introduction: Sporotrichosis is a mycosis caused by the fungus of the genus Sporothrix, of which six species related to human sporotrichosis are recognized, being the S. schenkii complex the most related to transmission in humans. The entry of the agent occurs by contact between the injured skin and the fungal spores, subsequently the fungal conidia are deposited in the host tissue and when introduced, become yeast. The fungus, now in its yeast-like phase, may remain at the site of entry or spread to other sites following the lymphatic vessels (1). Case presentation: We present the case of a 62-year-old male patient with arterial hypertension of 6 years of evolution, gardener, who came to our unit due to the presence of blistering and ulcerative lesions (image 1) on the foot and ipsilateral thigh. He received empirical treatment by private means with acyclovir cream and oxytetracycline, due to the characteristics of the lesions he was treated for herpes zoster with standard dose Acyclovir, he was seen in an outpatient internal medicine clinic one week later. Due to persistence of lesions and scarce reduction in symptomatology, a diagnosis was made according to clinical history, dermal and biochemical pattern of probable mycosis, with emphasis on sporotrichosis or “gardener's disease”, initiating treatment with itraconazole fractional dose for four weeks, with weekly follow-up of the case. Conclusions: At present, the diagnosis of S. schenkii, is of exclusion, in the face of predominant agents in the region. The most frequent clinical forms in humans are the fixed cutaneous form, the lymphatic form and the disseminated form; the latter has a poor prognosis due to its association with immunodeficiencies. Our case is an example of timely diagnosis with appropriate initial azole-based treatment, reflecting a successful case response, inviting the clinician to early integration

Zenodo (CERN European Organization for Nuclear Research)
Mexican Social Security Institute (MX)
Openalex Percentile: Top 42%
Fungal Infections and Studies
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Superficial Cutaneous Sporotrichosis, Report of a Case with Adequate Response · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS