Therapeutic Uses of Triphala in Traditional Indian Medicine and Its Interaction with the Gut Microbiome

Abstract: Triphala, a traditional Ayurvedic polyherbal formulation comprising Amalaki, Bibhitaki, and Haritaki, is renowned for its wide-ranging therapeutic uses, particularly in digestive health, detoxification, and immune modulation. Its key bioactive compounds, including tannins, flavonoids, and phenolic acids, exhibit antioxidant, anti-inflammatory, and antimicrobial properties. Triphala has shown significant interactions with the gut microbiome, promoting beneficial bacteria such as Lactobacillus and Bifidobacterium, enhancing short-chain fatty acid production, and restoring microbial balance. Mechanistic studies suggest it strengthens the gut barrier, reduces inflammation, and inhibits pathogenic microbes. Clinical and preclinical evidence supports its efficacy in regulating metabolism, improving gut health, and preventing diseases. While generally safe at recommended doses, careful consideration of potential side effects and interactions is necessary. Future research should focus on microbiome-specific clinical trials and the development of Triphala-based probiotics and nutraceuticals, paving the way for its integration into modern medicine for managing gut-related disorders and promoting overall health. Keywords: Ayurveda, triphala, gut microbiome, Amalaki (Emblica officinalis), Bibhitaki (Terminalia bellirica) and Haritaki (Terminalia chebula). Title: Therapeutic Uses of Triphala in Traditional Indian Medicine and Its Interaction with the Gut Microbiome Author: Akhila K Kumar, Shruti Banswal International Journal of Life Sciences Research ISSN 2348-313X (Print), ISSN 2348-3148 (online) Vol. 13, Issue 1, January 2025 - March 2025 Page No: 13-26 Research Publish Journals Website: www.researchpublish.com Published Date: 06-February-2025 DOI: https://doi.org/10.5281/zenodo.14823431 Paper Download Link (Source) https://www.researchpublish.com/upload/book/Therapeutic%20Uses%20of%20Triphala-06022025-1.pdf