INFLUENCE OF PHARMACIST-LED EDUCATION ON NON-ALCOHOLIC FATTY LIVER DISEASE

BACKGROUND: Non-alcoholic fatty liver is a condition characterized by excess lipid deposition in the hepatocytes of the liver without the excessive consumption of alcohol. The prevalence of NAFLD continues to increase in tandem with the rise of type 2 diabetes and obesity. MATERIALS AND METHODS: This is a prospective, cohort, and interventional study in which subjects were randomized into test and control groups by the block randomization method. The TyG index was calculated for all the patients to explore the relationship between the TyG index and NAFLD. The KAP questionnaire was administered to all the patients at baseline and three subsequent follow-ups. Patients in the test group received structured education at every follow-up on NAFLD, while the control group patients received only at the final follow-up. RESULTS: A significant reduction in the TyG index values was observed in the test group compared to that of the control group (p < 0.05), indicating improved glycemic and lipid control following pharmacist-led education. KAP scores showed a marked improvement in the test group with a significant increase in knowledge and practice regarding NAFLD management. The TyG index demonstrated a positive correlation with the presence and severity of NAFLD. Patients who received regular pharmacist-led counselling showed better adherence to lifestyle modifications and dietary recommendations. CONCLUSION: Pharmacist-led education significantly improves the understanding, management, and control of NAFLD by reducing the TyG index and enhancing patient compliance with lifestyle modifications. KEYWORDS: Fatty liver, non-alcoholic fatty liver disease, triglycerides-glucose index, patient counseling, diabetes, pharmacist intervention, lipid metabolism.