Formulation and Evaluation of Polyherbal Gel for Anti-Acne Treatment

Topical gels are homogenous, semi-solid preparations used in the treatment and cure of skin conditions. Because gels are more hydrophilic by nature, the medicine or active component was released quickly. Herbal formulations mean a dosage form containing one or more herbs to give various cosmetic or therapeutical activity. In the present study, due to its antibacterial properties, moringa is helpful in preventing acne breakouts on the skin. It also helps in removing blemishes, dark spots, pimples and blackheads. While, Withania Somnifera (Ashwagandha) having anti-inflammatory and anti-oxidant properties it is used for acne treatment. Ashwagandha can help to cure hyperpigmentation by controlling the over production of melanin in the skin. Thus, it is used to remove acne scars. Hence these two trees are used for the preparation of anti-acne gel. F1 to F6 batches are prepared of the anti-acne gel. From these F4 batch is the optimized batch, since its homogeneity is very good, there is no grittiness. The F4 batch has viscosity 4470 cp, Spreadability is 16.66 gm.cm /sec. F4 batch shows moderate activity against Staphylococcus aureus which is responsible for formation of acne.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-06-10
DOI
https://doi.org/10.5281/zenodo.15631278
Primary Topic
Phytochemicals and Medicinal Plants
Type
article
Field-Weighted Citation Impact
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article

Formulation and Evaluation of Polyherbal Gel for Anti-Acne Treatment

Zenodo (CERN European Organization for Nuclear Research)
Phytochemicals and Medicinal Plants
article

Formulation and Evaluation of Polyherbal Gel for Anti-Acne Treatment

article en

Abstract

Topical gels are homogenous, semi-solid preparations used in the treatment and cure of skin conditions. Because gels are more hydrophilic by nature, the medicine or active component was released quickly. Herbal formulations mean a dosage form containing one or more herbs to give various cosmetic or therapeutical activity. In the present study, due to its antibacterial properties, moringa is helpful in preventing acne breakouts on the skin. It also helps in removing blemishes, dark spots, pimples and blackheads. While, Withania Somnifera (Ashwagandha) having anti-inflammatory and anti-oxidant properties it is used for acne treatment. Ashwagandha can help to cure hyperpigmentation by controlling the over production of melanin in the skin. Thus, it is used to remove acne scars. Hence these two trees are used for the preparation of anti-acne gel. F1 to F6 batches are prepared of the anti-acne gel. From these F4 batch is the optimized batch, since its homogeneity is very good, there is no grittiness. The F4 batch has viscosity 4470 cp, Spreadability is 16.66 gm.cm /sec. F4 batch shows moderate activity against Staphylococcus aureus which is responsible for formation of acne.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 38%
Phytochemicals and Medicinal Plants
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