Biochemical Effect Of Helicobacter Pylori Infection On Immune Stress Biomarkers

Based on the paper, here's a comprehensive description: This study investigates the biochemical effects of Helicobacter pylori infection on immune stress biomarkers. The research examined 100 individuals (80 H. pylori-infected patients and 20 healthy controls) with ages ranging from under 20 to over 65 years. The study evaluated serum concentrations of several key biomarkers: - Anti-nuclear Antibodies (ANA)- Anti-Double Strand DNA (anti-ds DNA)- Interlukin-2 (IL-2)- Cortisol- Immunoglobulins (IgA, IgM, IgG, and IgE) The results revealed significant associations between H. pylori infection and increased levels of serum ANA, Anti-ds DNA, IL-2, IgM, IgA, IgG, and IgE. These immune stress biomarkers were identified as potential predictors or risk factors for gastritis, gastric cancer, and autoimmune disorders. The findings suggest that H. pylori infection may be responsible for immune system disturbance and autoimmune disorders. The research was conducted at Gamal Abdel naser General Hospital, involving patients from medicine and endemic medicine departments who presented with continuous pyloric burning symptoms and tested positive for H. pylori antigen in stool samples. This work contributes to understanding the relationship between H. pylori infection and immune system response, with implications for both diagnostic approaches and treatment strategies in gastroenterology and immunology.