RSUP SANGLAH'S EXPERIENCE WITH GIANT CELL TUMORS OF BONE: A CLINICAL AND HISTOPATHOLOGICAL STUDY

Giant cell tumors of bone (GCTB) are kind of benign tumors with potential of aggressive and capability to metastase. GCTB is more common in Asia and occur around the knee. In Asia, most cases shown in men. Curettage alone has been the standard treatment for GCTB, but it has been associated with a relatively high risk of local recurrence ranging up to 35–40%. The study was cross sectional conducted with retrospective descriptive design. Samples of 38 patients diagnosed with Giant Cell Tumor of Bone (GCTB) at the Sanglah Hospital Denpasar Medical Record Installation, Bali for the period 2015-2019 were selected based on inclusion and exclusion criteria. Data were analyzed using SPSS software to obtain distribution, frequency based on age, sex, tumor location, mitotic activity, recurrency. The case of giant cell tumor of bone (GCTB) of bone at Sanglah General Hospital Denpasar Bali in 2015-2019 was 38 people, the patient characteristics were mostly women (65,8%) with an age range dominated by the 2nd to 4th decade or life (47.4%). Characteristics of GCT of bone indicate the location of the distal femur is the most common case (26,3%) with mitotic activity of 1 and 3 per 10 hpfs and only 5.3% of cases of recurrent GCTB. It was concluded that the case of gian cell tumor of bone (GCTB) of bone at Sanglah General Hospital Denpasar Bali in 2015-2019 mostly women (21-40) and the location of the distal femur is the most common case with mitotic activity of 1 and 3 per 10 hpfs and only 5.3% of cases of recurrent GCTB.