LONG-TERM OUTCOMES OF DEEP BRAIN STIMULATION IN PATIENTS WITH PARKINSON'S DISEASE

Deep Brain Stimulation (DBS) has established itself over the past two decades as an effective method for comprehensive treatment of Parkinson's disease when conservative therapy proves ineffective or insufficiently effective. The method is based on the implantation of electrodes into specific brain structures (predominantly the subthalamic nucleus, globus pallidus, or ventral intermediate nucleus of the thalamus) with subsequent activation through a subcutaneously implanted neurostimulator. Electrical stimulation modulates pathological neuronal activity in the basal ganglia, which leads to a reduction in the main motor symptoms of the disease and allows for a significant decrease in the dosage of antiparkinsonian medications.